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Credentialing Guidelines and Requirements

A Candidate Guidebook

Immunization Administration Assessment-Based Certificate Program

Immunization Administration Certificate Program


PTCB Immunization Administration Certificate holders have demonstrated their advanced skills and commitment to patient and community care by minimizing the spread of disease in the community, especially as vaccines are delivered in massive quantities to prevent the spread of COVID-19.

Eligibility Requirements

A candidate must hold an active PTCB CPhT Certification and complete a PTCB-Recognized Immunization Administration Education/Training Program.


Candidates are required to pass the Immunization Administration Exam to earn the PTCB Immunization Administration Certificate. The Immunization Administration Exam is a multiple-choice exam that contains 60 questions. Be prepared to commit 1 hour and 30 minutes for the exam (5-minute tutorial, and 1 hour and 20-minute exam, and 5-minute post-exam survey).

Exam Content Outline

The Immunization Administration Exam covers several knowledge areas organized into three domains, as shown in the following table.

Concepts/ Terminology of Vaccine Administration (30%)
Roles of pharmacy technicians in supporting immunizations
Definition of key terms in the immunization process (e.g., active vs. passive immunity, inactivated vs. LAV)
Common vaccinations and vaccination schedules (e.g., influenza, zoster, Pneumococcal, Tdap)
Vaccine Safety and Administration (50%)
Preparation for vaccine administration, including supply selection (e.g., reconstitution, needle length)
Procedures for vaccine administration: SQ, IM, IN
Safety considerations during vaccine administration (e.g., handling and disposal of sharps)
Documentation, Product Handling, and Adverse Reaction Management for Vaccines (20%)
Procedures for immunization-related documentation (e.g., VIS form)
Procedures for receiving, storing, and handling of vaccines (e.g., cold chain, disposal)
Managing vaccine-related adverse reactions and emergency situations (e.g., localized reactions, syncope, anaphylaxis, VAERS vs. VERP)

Exam Passing Score

On November 16, 2021 PTCB published an updated version of the Immunization Administration Exam. Scores will be withheld for six weeks as PTCB applies a rigorous process to ensure that scoring of the updated exam is equivalent to the previous version.


Earning your Immunization Administration Certificate takes you one step closer to becoming a PTCB Advanced Certified Pharmacy Technician (CPhT-Adv). Active PTCB CPhTs who have completed at least four of the certificate programs (must include TPV or Medication History), or three certificate programs and the Compounded Sterile Preparation Technician (CSPT) Certification, and 3 years of work experience will be eligible to earn a CPhT-Adv credential.